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Dexmedetomidine effects on shivering and core temperature in awake normal subjects
Internal Dataset

UID: 3

Author(s): Callaway, Clifton W.*+ * Corresponding Author + University of Pittsburgh Author
Description
Ten normal adult human subjects received a rapid intravenous infusion of two liters of cold (4ºC) isotonic saline on two separate test days, and we measured their core body temperature, shivering, hemodynamics and sedation for two hours. On one test day, fluid infusion was preceded by placebo infusion. On the other test day, fluid infusion was preceded by 1.0 µg/kg bolus of dexmedetomidine over 10 minutes.
Subject of Study
Humans
Population Age
Adult
Subject Gender
Male
Female
Keywords
Dexmedetomidine
Emergency Medicine
Heart Rate
Myocardial Infarction
Precedex
Shivering
Access via Zenodo

Includes shivering assessment scales, comfort scales, Richmond agitation scales, physiologic data
Accession #: http://doi.org/10.5281/zenodo.18489

Access Restrictions
Free to all
Access Instructions
Access via Zenodo
Associated Publications
Callaway CW, Elmer J, Guyette FX, Molyneaux BJ, Anderson KB, Empey PE, et al. Dexmedetomidine Reduces Shivering during Mild Hypothermia in Waking Subjects. PLoS One. 2015 Aug 3;10(8):e0129709. doi: 10.1371/journal.pone.0129709. PMID: 26237219; PMCID: PMC4523180.
Data Type
Clinical Measures
Dataset Format(s)
CSV (.csv)
Resource Type(s)
Dataset
Grant Support
K12 HL109068/NHLBI
Data Catalog Record Updated
2018-05-01

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