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  • Internal Dataset

    Data from: Monkeys exhibit a paradoxical decrease in performance in high-stakes scenarios

    Authors
    • Smoulder, Adam L.
    • Pavlovsky, Nicholas P.
    • Marino, Patrick J.
    • Degenhart, Alan D.
    • 3 more author(s)...
    Description

    This dataset includes pre-processed reaching movement kinematic data generated by three adult male rhesus monkeys (Macaca mulatta). The animals were trained to perform a challenging delayed-reaching task in which they knew in advance the magnitude of the reward they would earn for a successful movement. The experiments were conducted to determine whether nonhuman animals "choke under pressure" (perform...

    Keywords
    • Behavior, Animal
    • Macaca mulatta
    • Motivation
    • Motor Skills
    • Psychomotor Performance
    • Reward
    Access Rights
    Free to all
  • Internal Dataset

    Targeted deletion of astrocytic Nhe1 stimulates Wnt/β-catenin-mediated BBB repair and angiogenesis after ischemic stroke

    Authors
    • Begum, Gulnaz
    • Sun, Dandan
    • Chattopadhyay, Ansuman
    • Chaparala, Srilakshmi
    Description

    Examination of effect of deletion of astrocytic Na+/H+ exchanger isoform 1 (Nhe1) on post-stroke recovery and vascular repair. Expression profiling by high throughput sequencing of astrocytes from Gfap-CreERT2+/-;Nhe1f/f mouse brains, 24 hours after transient middle cerebral artery occlusion. Twelve NCBI GEO records: 3 samples each from Wild-type and Nhe1 Astro-KO, both contralateral and ipsilateral....

    Keywords
    • Angiogenesis
    • Astrocytes
    • Blood-Brain Barrier
    • Cerebrovascular Circulation
    • Gene Expression Profiling
    • High-Throughput Nucleotide Sequencing
    • Ischemic Stroke
    • Mus musculus
    • RNA-Seq
    Access Rights
    Free to all
  • Internal Dataset

    Data from: HIV infection is an independent risk factor for decreased 6-minute walk test distance

    Authors
    • Robertson, Tom E.
    • Nouraie, Mehdi
    • Qin, Shulin
    • Crothers, Kristina A.
    • 8 more author(s)...
    Description

    This dataset represents "the minimal underlying data that an independent researcher would need in order to replicate the results” from the associated study which assessed the independent effect of HIV on subjective and objective measures of cardiac and pulmonary function. Adult (18 years or older) persons living with HIV (PLWH) and HIV-uninfected individuals were recruited from the University...

    Keywords
    • HIV
    • HIV Infections
    • Lung
    • Lung Diseases
    • Respiratory Function Tests
    • Risk Factors
    • Walk Test
    Access Rights
    Free to all
  • Internal Dataset

    All of Us Research Hub

    Description

    With an emphasis on reaching historically underrepresented populations, the datasets from the All of Us Research Program include: Electronic health records (OMOP CDM used to standardize all EHR data) Biosamples (blood, urine, and saliva) Mobile health data (from wearable devices that may track biometric data like heart rate and blood pressure) Physical measurements (height, weight, BMI,...

    Keywords
    • Cohort Studies
    • Demography
    • Electronic Health Records
    • Health Status
    • Healthcare Disparities
    • Population Characteristics
    • Populations, Underserved
    • Public Health Surveillance
    • Risk Factors
    • Vulnerable Populations
    Timeframe
    2017 – Present
    Access Rights
    Free to all
    Application required
    Fee required
  • Internal Dataset

    Data on early assessment of knowledge, attitudes, and behavioral responses to COVID-19 among Connecticut residents

    Authors
    • Ha, Toan H.
    • Schensul, Stephen L.
    Description

    This dataset was generated from a survey that assessed participants’ knowledge, perceived risk, perceived seriousness, anxiety, adoption of prevention behaviors and source of information related to COVID-19. The survey was conducted anonymously among a non-random sample of 464 Connecticut residents in the early stage of social distancing and shutdown from March 23 to March 29, 2020. Participants...

    Keywords
    • Communicable Diseases
    • COVID-19
    • Health Behavior
    • SARS-CoV-2
    Timeframe
    2020
    Access Rights
    Free to all
  • Internal Dataset

    Characterizing the effect of feeding distension and emetic stimuli on gastric myoelectric activity in ferrets

    Authors
    • Nanivadekar, Ameya
    • Miller, Derek M.
    • Fulton, Stephanie
    • McLaughlin, Bryan
    • 2 more author(s)...
    Description

    From the authors: This dataset contains gastric myoelectric activity recorded from multi-electrode arrays, surgically implanted on the serosal surface of the GI tract to study perturbations due to mechanical or chemical stimuli in acute and chronic preparations of ferrets. This dataset comprises 20,315 myoelectric waveform files recording nausea and emesis in ferrets (Mustela putorius). The dataset...

    Keywords
    • Electromyography
    • Electrophysiology
    • Ferrets
    • Gastrointestinal Tract
    • Machine learning
    • Nausea
    • Vagus Nerve Stimulation
    • Vomiting
    Access Rights
    Free to all
    Fee required
  • Internal Dataset

    MutantHuntWGS

    Authors
    • Ellison, Mitchell A.
    • Walker, Jennifer L.
    • Ropp, Patrick J.
    • Durrant, Jacob D.
    • 1 more author(s)...
    Description

    This Github repository contains a bioinformatics pipeline for identification and characterization of mutations in Saccharomyces cerevisiae. MutantHuntWGS compares data, input in FASTQ format, from a mutant strain to a wild-type strain to identify high confidence sequence variants present only in the mutant. To enable quick and easy installation and to ensure reproducibility, MutantHuntWGS was...

    Keywords
    • Saccharomyces cerevisiae
    • Sequence Alignment
    • Variant Calling
    • Whole Genome Sequencing
    Access Rights
    Free to all
  • Internal Dataset

    Data from: SARS-CoV-2 Infections - Gene Expression Omnibus (GEO) Data Mining, Pathway Enrichment Analysis, and Prediction of Potentially Repurposable Drugs

    Authors
    • Chaparala, Srilakshmi
    • Iwema, Carrie L.
    • Chattopadhyay, Ansuman
    Description

    This project describes a protocol to analyze publicly available transcriptomic data from the NCBI Gene Expression Database (GEO) using in silico approach. This involved identifying SARS-CoV-2 infection-induced differentially Expressed (DE) genes from human gene mapping and viral mapping, statistically enriched pathway associations, and potentially repurposable drugs for COVID-19 treatment. Further...

    Keywords
    • COVID-19
    • Gene Expression Profiling
    • SARS-CoV-2
    • Sequence Analysis, RNA
    • Transcriptomics
    • Virus Diseases
    Access Rights
    Free to all
  • Internal Dataset

    Data from: Apologies as signals for change? Implicit theories of personality and reactions to apologies during the #MeToo movement

    Authors
    • Schumann, Karina
    Description

    This dataset was generated from a survey of 720 participants (366 females, 354 males) recruited from Qualtrics in December of 2017 when the #MeToo movement was still at its peak. The survey examined people's reactions to apologies offered by prominent public figures in response to allegations of sexual misconduct (ranging from sexual harassment to rape) with a focus on whether their implicit theories...

    Keywords
    • Forgiveness
    • Personality
    • Psychology
    • Sex Offenses
    • Social Perception
    Timeframe
    2017
    Access Rights
    Free to all
  • Internal Dataset

    Project Tycho

    Authors
    • Van Panhuis, Willem
    • Cross, Anne
    • Burke, Donald
    Description

    Project Tycho provides open global health data through three channels: Pre-compiled datasets: 360 datasets of case counts for 92 conditions within the United States, and for dengue-related conditions globally Compile your own: a search interface for compiling data related to 92 health conditions in 99 countries Application programming interface: an API for enabling data access for computer programs Project...

    Keywords
    • Dengue
    • Epidemiology
    • Global Health
    • Mortality
    • Prevalence
    • Public Health Surveillance
    Access Rights
    Free to all with registration