Data and code are provided for an fMRI study examining brain function among adolescents and young adults during an anti-saccade (deliberately looking away from a target) task. The data package on OpenNeuro includes sex and age information for 28 participants, eye movement data, defaced resting-state anatomy scans, defaced imaging data collected for the task, a README, and a JSON file containing metadata for the anti-saccade task. The Github repository hosts data processing and analysis scripts.
From the abstract: "The nature of immature reward processing and the influence of rewards on basic elements of cognitive control during adolescence are currently not well understood. Here, during functional magnetic resonance imaging, healthy adolescents and adults performed a modified antisaccade task in which trial-by-trial reward contingencies were manipulated. The use of a novel fast, event-related design enabled developmental differences in brain function underlying temporally distinct stages of reward processing and response inhibition to be assessed. Reward trials compared with neutral trials resulted in faster correct inhibitory responses across ages and in fewer inhibitory errors in adolescents. During reward trials, the blood oxygen level–dependent signal was attenuated in the ventral striatum in adolescents during cue assessment, then overactive during response preparation, suggesting limitations during adolescence in reward assessment and heightened reactivity in anticipation of reward compared with adults. Importantly, heightened activity in the frontal cortex along the precentral sulcus was also observed in adolescents during reward-trial response preparation, suggesting reward modulation of oculomotor control regions supporting correct inhibitory responding. Collectively, this work characterizes specific immaturities in adolescent brain systems that support reward processing and describes the influence of reward on inhibitory control. In sum, our findings suggest mechanisms that may underlie adolescents’ vulnerability to poor decision-making and risk-taking behavior."
Behavioral data captured from eye tracking, anatomy scan, and anti-saccade task fMRI images
Accession #: ds000121
Data-processing bash scripts
Long-range optic eye tracking system
3-Tesla MRI scanner
Software for displaying controlled stimuli.
Comprehensive library of analysis tools for FMRI, MRI and DTI brain imaging data.
Eye movement analysis software
Numerical computing environment and programming language.
Tool for extracting image quality metrics for quality assessment of MRI data.
Defacing tool for fMRI data.
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