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  • Internal Dataset

    Targeted deletion of astrocytic Nhe1 stimulates Wnt/β-catenin-mediated BBB repair and angiogenesis after ischemic stroke

    Authors
    • Begum, Gulnaz
    • Sun, Dandan
    • Chattopadhyay, Ansuman
    • Chaparala, Srilakshmi
    Description

    Examination of effect of deletion of astrocytic Na+/H+ exchanger isoform 1 (Nhe1) on post-stroke recovery and vascular repair. Expression profiling by high throughput sequencing of astrocytes from Gfap-CreERT2+/-;Nhe1f/f mouse brains, 24 hours after transient middle cerebral artery occlusion. Twelve NCBI GEO records: 3 samples each from Wild-type and Nhe1 Astro-KO, both contralateral and ipsilateral....

    Keywords
    • Angiogenesis
    • Astrocytes
    • Blood-Brain Barrier
    • Cerebrovascular Circulation
    • Gene Expression Profiling
    • High-Throughput Nucleotide Sequencing
    • Ischemic Stroke
    • Mus musculus
    • RNA-Seq
    Access Rights
    Free to all